New study reveals

Semaglutive medicines like Ozempic and Wegovy have exploited in recent years due to their effectiveness in controlling diabetes and weight loss.

The research has revealed additional benefits beyond these primary uses, but some negative side effects have also emerged.

While gastrointestinal problems are the most common side effects, a recent study from the University of British Columbia linked GLP-1 agonists (peptides-1) (peptides-1)) (the class of drugs that includes semaglutides) with an increase in the risk of hair loss.

Researchers analyzed 16 million patients from a health claim database, reducing it to 1,926 semaglutid users and 1,348 Buppropion-Naltrexone users, another type of weight loss medication.

After adjusting to other factors, they found that semaglutides were 50% more likely to suffer from hair loss compared to the other group.

Women were more likely to have this result, twice the risk of men.

“It’s not surprising”

The researchers were not surprised by the results, according to the co-study of Dr. Mahyar Etminan, epidemiologist and CEO of Epilics in Vancouver, British Columbia, Canada.

Generally, semaglutid users were 50% more likely to suffer from hair loss compared to the other group. Mbruxelle – Stock.adobe.com

“There was [previous] The anecdotal reports of hair loss and also report hair loss in clinical trials of drugs, “Fox News Digital told Fox.

Dr. Patrick Davis, a plastic surgeon from Beverly Hills and a hair restoration expert, agreed that the findings were not surprising.

“We have heard it anecdotally when patients consult us for the surgical restoration of the face after a quick weight loss,” he said in an interview with Fox News Digital.

“Hair growth (and loss) depends on factors such as diet, essential vitamins, body stress and genetics.”

The first three factors come into play during weight loss, said: “And the loss driven by semaglutides is no exception.”

Previous studies have shown that changes that induce stress or affect nutritional intake may increase the risk of hair loss, added the doctor.

“This study refers to those who lost more than 20% of their body weight had higher hair loss rates than those that did not,” said Davis.

“This study theorizes that this may be due to a suspicious physiological stress, which may be a sign of such a quick weight loss.”

The doctor said long -term hair loss is more unlikely, as the “inciting event” (weight loss and stress) is often normalized as individuals reach their target weight.

Potential limitations

The study had some limitations, said researcher Etminan.

These included the fact that they could not verify hair loss through medical records, but only identified medical codes for hair loss.

The doctor said long -term hair loss is more unlikely, as the “inciting event” (weight loss and stress) is often normalized as individuals reach their target weight. BlackDay – Stock.adobe.com

Davis, the plastic surgeon, also said that this research refers to another study in which Wegovy users were at a high risk of hair loss (3.3%) compared to the placebo group (1.4%).

“Although this clearly shows an increased risk, 3.3% is still a very low incidence rate,” he said.

This early study, published on the Preprint Medrxiv server, has not yet been reviewed by equals.

“Future studies are needed to check the association between semaglutide and hair loss,” the researchers wrote.

Doctors’ Tips

Those who experience hair loss while taking semagluted medicine must consult with a dermatologist to determine if it is due to a negative effect of these medicines, he advised etminan.

“This is a relatively new adverse event, and it is not known much,” he said. “Questions about who is at risk and if hair loss will reverse when stopping the drug can be addressed in future studies.”

Davis agreed, encouraging patients to talk open with their doctor about how they can better take care of them.

“I think a patient should consider the possible side effects before taking any medicine,” he said.

“Although the rate of incidence of hair loss is still decidedly low, it is a possible commitment that a patient should consider.”

Davis also recommends that his patients take a “abundant diet” formed by fiber, proteins and nutritional foods to ensure proper nutrition while taking a semaglutin medicine.

“Not only that can help hair loss, but a strong diet can slow down the unwanted loss of muscle mass that is often produced,” he said. “An appropriate diet, the conservative calendar for weight loss and the plan for exercise are essential when taking this drug.”

When contacted by Fox News Digital, Novo Nordisk, a manufacturer of Ozempic and Wegovy, confirmed that hair loss is an identified risk by semaglutid and is shown as a side effect on product information.

“Future studies are needed to check the association between semaglutide and hair loss,” the researchers wrote. Myskin – Stock.adobe.com

“In Wegovy’s clinical trials, he was reported to 2.5% of the adult patients treated with Wegovy compared to 1.0% of the adult patients treated with placebo,” said company spokesman.

“Hair loss was more frequently reported in higher weight loss patients (≥20%), suggesting that hair loss events were potentially related to the magnitude of weight loss.”

“The patient’s safety is of the highest importance for Novo Nordisk,” the statement continued. “We constantly monitor the security profile of our products and collaborate closely with the authorities to ensure patient safety, including appropriate hair loss information.”

The study was funded by the Department of Ophthalmology and Visual Sciences Department of the University of the British Columbia, according to the article in the magazine.

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